SCN1A Polyclonal Antibody | G-AB-01482

SCN1A Polyclonal Antibody | G-AB-01482 | Gentaur Antibodies

Overview: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience

Synonyms: brain sodium channel type I, EIEE6, FEB3, FEB3A, FHM3, GEFS+2, GEFSP2, HBSC I, HBSCI, NAC1, Nav 1.1, RBI, SCN1, Scn1a, SCN1A, SMEI, Sodium channel protein brain I alpha subunit, Sodium channel protein brain I subunit alpha, Sodium channel protein type 1 subunit alpha, Sodium channel protein type I subunit alpha, Sodium channel voltage gated type 1 alpha subunit, Sodium channel voltage gated type I alpha polypeptide, Voltage-gated sodium channel subunit alpha Nav1.1

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_001159435

Clonality: Polyclonal

Immunogen: Synthetic peptide of human SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/12A

Clone #:

Conjugation: Unconjugated

Swissprot: P35498

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SCN1A Polyclonal Antibody DataSheet