SF1 Polyclonal Antibody | G-AB-11090

SF1 Polyclonal Antibody | G-AB-11090 | Gentaur Antibodies

Overview: This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF) , and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: SF1, BBP, D11S636, MBBP, ZCCHC25, ZFM1, ZNF162

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 7536

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SF1 (NP_973727.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q15637

Santa Cruz:

Calculated MW: 59 kDa/61 kDa/65 kDa/67 kDa/68 kDa/71 kDa

Observed MW: 68 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SF1 Polyclonal Antibody DataSheet