SH-PTP2 Polyclonal Antibody | G-AB-02116
Gentaur Antibodies
- SKU:
- G-AB-02116
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
SH-PTP2 Polyclonal Antibody | G-AB-02116 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Neuroscience, Signal Transduction
Synonyms: BPTP3, CFC, JMML, METCDS, MGC14433, NS1, OTTHUMP00000166107, OTTHUMP00000166108, Protein tyrosine phosphatase 2, Protein tyrosine phosphatase 2C, Protein tyrosine phosphatase non receptor type 11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, PTN11, PTP-1D, PTP-2C, PTP1D, PTP2C, PTPN11, SAP2, SH-PTP2, SH-PTP3, SH2 domain containing protein tyrosine phosphatase 2, SHP 2, SHP-2, Shp2, SHPTP2, SHPTP3, Syp, Tyrosine-protein phosphatase non-receptor type 11
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC008692
Clonality: Polyclonal
Immunogen: Recombinant protein of human PTPN11
Clone #:
Conjugation: Unconjugated
Swissprot: Q06124
Santa Cruz: sc-30687/sc-30688/sc-30689/sc-280/sc-424
Calculated MW: 68 kDa
Observed MW:
Concentration: 0.3 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, ELISA
Dilution: WB 1:200-1:1000
Storage: Store at -20°C. Avoid freeze / thaw cycles.