SIGLEC8 Polyclonal Antibody | G-AB-07409

SIGLEC8 Polyclonal Antibody | G-AB-07409 | Gentaur Antibodies

Overview: Sialic acid-binding immunoglobulin (Ig) -like lectins, or SIGLECs, are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964) , and a motif homologous to one identified in signaling lymphocyte activation molecule that mediates an association with SLAM-associated protein .

Category Type: Polyclonal Antibody

Research Areas: Immunology, Signal Transduction

Synonyms: SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 27181

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SIGLEC8 (NP_055257.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NYZ4

Santa Cruz:

Calculated MW: 44 kDa/46 kDa/54 kDa

Observed MW: 60 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SIGLEC8 Polyclonal Antibody DataSheet