SLC22A17 Polyclonal Antibody | G-AB-02939

SLC22A17 Polyclonal Antibody | G-AB-02939 | Gentaur Antibodies

Overview: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3) , followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3) , followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: 24p3 receptor, 24p3R, BOCT, BOIT, Brain type organic cation transporter, Brain-type organic cation transporter, hBOIT, Lipocalin-2 receptor, Neutrophil gelatinase associated lipocalin receptor, Neutrophil gelatinase-associated lipocalin receptor, NGAL receptor, NgalR, NGALR2, NGALR3, OTTHUMP00000082690, OTTHUMP00000082691, Potent brain type organic ion transporter, S22AH, Slc22a17, Solute carrier family 22 member 17, Solute carrier family 22 organic cation transporter member 17

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_065105.2

Clonality: Polyclonal

Immunogen: Synthetic peptide of human SLC22A17

Clone #:

Conjugation: Unconjugated

Swissprot: Q8WUG5

Santa Cruz: sc-138147/sc-138148

Calculated MW: 56 kDa

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SLC22A17 Polyclonal Antibody DataSheet