SLC4A4 Polyclonal Antibody | G-AB-02121

SLC4A4 Polyclonal Antibody | G-AB-02121 | Gentaur Antibodies

Overview: This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. Sodium bicarbonate cotransporters (NBCs) mediate the coupled movement of sodium and bicarbonate ions across the plasma membrane of many cells. This is an electrogenic process with an apparent stoichiometry of 3 bicarbonate ions per sodium ion. Sodium bicarbonate cotransport is involved in bicarbonate secretion/absorption and intracellular pH regulation. Romero and Boron (1999) reviewed NBCs. Soleimani and Burnham (2000) reviewed NBCs and their regulation in physiologic and pathophysiologic states.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Neuroscience, Signal Transduction

Synonyms: DKFZp781H1314, Electrogenic sodium bicarbonate cotransporter 1, hhNMC, HNBC 1, HNBC1, kNBC 1, KNBC, kNBC1, Na (+) /HCO3 (-) cotransporter, Na+HCO3- cotransporter 4, NBC 1, NBC 2, NBC1, NBC2, Nbc4, NBCE 1, NBCE1, OTTHUMP00000160355, OTTHUMP00000218884, OTTHUMP00000218885, PNBC, S4A4, SLC4A4, SLC4A5, Sodium bicarbonate cotransporter 1 (sodium bicarbonate cotransporter, kidney, sodium bicarbonate cotransporter, pancreas) , Sodium bicarbonate cotransporter, Sodium bicarbonate cotransporter kidney, sodium bicarbonate cotransporter member 4, Sodium bicarbonate cotransporter pancreas, Solute carrier family 4 member 4, Solute carrier family 4 sodium bicarbonate cotransporter member 4, Solute carrier family 4 sodium bicarbonate cotransporter member 5, Solute carrier family 4, sodium bicarbonate cotransporter, member 4, brain type

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC030977

Clonality: Polyclonal

Immunogen: Recombinant protein of human SLC4A4

Clone #:

Conjugation: Unconjugated

Swissprot: Q9Y6R1

Santa Cruz: sc-162214/sc-162215/sc-162216

Calculated MW:

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SLC4A4 Polyclonal Antibody DataSheet