SMAD7 Polyclonal Antibody | G-AB-02857

SMAD7 Polyclonal Antibody | G-AB-02857 | Gentaur Antibodies

Overview: The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1) , leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3) . Several transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: CRCS3, FLJ16482, hSMAD 7, hSMAD7, MAD (mothers against decapentaplegic Drosophila) homolog 7, MAD, Mad homolog 7, MAD homolog 8, MAD mothers against decapentaplegic homolog 7, MADH 7, MADH 8, MADH6, MADH8, Mothers Against Decapentaplegic Drosophila Homolog of 6, Mothers Against Decapentaplegic Drosophila Homolog of 7, Mothers against decapentaplegic homolog 7, Mothers against decapentaplegic homolog 8, Mothers against DPP homolog 7, Mothers against DPP homolog 8, SMA- AND MAD-RELATED PROTEIN 7, SMAD 7, SMAD, SMAD family member 7, SMAD, mothers against DPP homolog 7 (Drosophila) , SMAD, mothers against DPP homolog 7, SMAD6, Smad7, SMAD7

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_005895

Clonality: Polyclonal

Immunogen: Synthetic peptide of human SMAD7

Clone #:

Conjugation: Unconjugated

Swissprot: O15105

Santa Cruz: sc-9183/sc-7004/sc-11392/sc-134013

Calculated MW:

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SMAD7 Polyclonal Antibody DataSheet