SMAD7 Polyclonal Antibody | G-AB-07407
Gentaur Antibodies
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Gentaur Antibodies
SMAD7 Polyclonal Antibody | G-AB-07407
- SKU:
- G-AB-07407
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
SMAD7 Polyclonal Antibody | G-AB-07407 | Gentaur Antibodies
Overview: The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1) , leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3) . Several transcript variants encoding different isoforms have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Synonyms: SMAD7, CRCS3, MADH7, MADH8
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 4092
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human SMAD7 (NP_005895.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: O15105
Santa Cruz:
Calculated MW: 23 kDa/46 kDa
Observed MW: 46 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:500-1:1000 IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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