SNAP23 Polyclonal Antibody | G-AB-08479

SNAP23 Polyclonal Antibody | G-AB-08479 | Gentaur Antibodies

Overview: Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa) , form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience

Synonyms: SNAP23, HsT17016, SNAP-23, SNAP23A, SNAP23B

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8773

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SNAP23 (NP_003816.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O00161

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:100-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SNAP23 Polyclonal Antibody DataSheet