SOCS2 Polyclonal Antibody | G-AB-09622
Gentaur Antibodies
- SKU:
- G-AB-09622
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
SOCS2 Polyclonal Antibody | G-AB-09622 | Gentaur Antibodies
Overview: This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway) . SOCS family proteins interact with major molecules of signaling complexes to block further Signal Transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN) -gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Immunology, Neuroscience, Signal Transduction
Synonyms: SOCS2, CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 8835
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human SOCS2 (NP_001257400.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: O14508
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.