SPTLC1 Polyclonal Antibody | G-AB-11298

SPTLC1 Polyclonal Antibody | G-AB-11298 | Gentaur Antibodies

Overview: This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Synonyms: SPTLC1, HSAN1, HSN1, LBC1, LCB1, SPT1, SPTI

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 10558

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SPTLC1 (NP_006406.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O15269

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SPTLC1 Polyclonal Antibody DataSheet