SSX4 Polyclonal Antibody | G-AB-11952

SSX4 Polyclonal Antibody | G-AB-11952 | Gentaur Antibodies

Overview: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: SSX4, CT5.4

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 6759

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SSX4 (NP_005627.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O60224

Santa Cruz:

Calculated MW: 17 kDa/21 kDa

Observed MW: 27 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SSX4 Polyclonal Antibody DataSheet