SYT4 Polyclonal Antibody | G-AB-02135
Gentaur Antibodies
- SKU:
- G-AB-02135
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
SYT4 Polyclonal Antibody | G-AB-02135 | Gentaur Antibodies
Overview: Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus. The proximity of the Synaptotagmin IV gene to markers of several psychiatric disorders suggest an involvement of synaptotagmin IV in human disease. Synaptotagmin V is a dense-core vesicle-specific protein that regulates a specific type of calcium-regulated secretion. Synaptotagmin VI interacts with adaptor protein-2 in a calcium-independent manner. Synaptotagmin VII is widely expressed in non-neuronal tissues.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Neuroscience, Signal Transduction
Synonyms: HsT1192, KIAA1342, Synaptotagmin IV, Synaptotagmin4, SynaptotagminIV, SYT 4, Syt IV, SYT4, SytIV
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC036538
Clonality: Polyclonal
Immunogen: Recombinant protein of human SYT4
Clone #:
Conjugation: Unconjugated
Swissprot: Q9H2B2
Santa Cruz: sc-14446/sc-27624/sc-27625/sc-27624/sc-27625/sc-30095/sc-30095
Calculated MW: 48 kDa
Observed MW:
Concentration: 0.2 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, IHC, ELISA
Dilution: WB 1:500-1:2000, IHC 1:25-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.