SYT4 Polyclonal Antibody | G-AB-11837

SYT4 Polyclonal Antibody | G-AB-11837 | Gentaur Antibodies

Overview: Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus. The proximity of the Synaptotagmin IV gene to markers of several psychiatric disorders suggest an involvement of synaptotagmin IV in human disease. Synaptotagmin V is a dense-core vesicle-specific protein that regulates a specific type of calcium-regulated secretion. Synaptotagmin VI interacts with adaptor protein-2 in a calcium-independent manner. Synaptotagmin VII is widely expressed in non-neuronal tissues.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction

Synonyms: SYT4, HsT1192

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6860

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SYT4 (NP_065834.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9H2B2

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SYT4 Polyclonal Antibody DataSheet