TAPBP Polyclonal Antibody | G-AB-09859

TAPBP Polyclonal Antibody | G-AB-09859 | Gentaur Antibodies

Overview: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP) , which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Immunology, Signal Transduction

Synonyms: TAPBP, NGS17, TAPA, TPN, TPSN, tapasin

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6892

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human TAPBP (NP_757345.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O15533

Santa Cruz:

Calculated MW: 38 kDa/43 kDa/47 kDa/53 kDa

Observed MW: 48 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TAPBP Polyclonal Antibody DataSheet