TDP1 Polyclonal Antibody | G-AB-11981
Gentaur Antibodies
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Gentaur Antibodies
TDP1 Polyclonal Antibody | G-AB-11981
- SKU:
- G-AB-11981
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
TDP1 Polyclonal Antibody | G-AB-11981 | Gentaur Antibodies
Overview: The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1) .
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: TDP1
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 55775
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human TDP1 (NP_060789.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q9NUW8
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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