TGFB2 Polyclonal Antibody | G-AB-00367
Gentaur Antibodies
- SKU:
- G-AB-00367
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
TGFB2 Polyclonal Antibody | G-AB-00367 | Gentaur Antibodies
Overview: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t (1;7) (q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.
Category Type: Polyclonal Antibody
Research Areas: Signal Transduction, Stem Cells, Cancer, Metabolism
Synonyms: BSC1 cell growth inhibitor, Cetermin, G-TSF, Glioblastoma-derived T-cell suppressor factor, GTSF, LAP, Latency-associated peptide, MGC116892, MGF, Milk growth factor, Polyergin, TGF-beta2, TGFB2, Transforming growth factor beta 2
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 7042
Accession #:
Clonality: Polyclonal
Immunogen: Recombinant Human Transforming growth factor beta-2 proprotein protein
Clone #:
Conjugation: Unconjugated
Swissprot: P61812
Santa Cruz:
Calculated MW: 47, 50 kDa
Observed MW: 47 kDa
Concentration: 0.95 mg/mL
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3
Purification method: Antigen Affinity Purification
Application: WB, IHC
Dilution: WB 1:500-1:2000 IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.