TGFBR2 Polyclonal Antibody | G-AB-07635

TGFBR2 Polyclonal Antibody | G-AB-07635 | Gentaur Antibodies

Overview: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction, Stem cells

Synonyms: AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII, TGF beta Receptor II, TGFBR2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 7048

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human TGFBR2 (NP_003233.4) .

Clone #:

Conjugation: Unconjugated

Swissprot: P37173

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TGFBR2 Polyclonal Antibody DataSheet