THPO Polyclonal Antibody | G-AB-09765

THPO Polyclonal Antibody | G-AB-09765 | Gentaur Antibodies

Overview: Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Stem Cells

Synonyms: THPO, MGDF, MKCSF, ML, MPLLG, THCYT1, TPO

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 7066

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human THPO (NP_001171068.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P40225

Santa Cruz:

Calculated MW: 33 kDa/37 kDa

Observed MW: 32 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

THPO Polyclonal Antibody DataSheet