TLR5 Polyclonal Antibody | G-AB-09671

TLR5 Polyclonal Antibody | G-AB-09671 | Gentaur Antibodies

Overview: This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: MELIOS, SLE1, SLEB1, TIL3, TLR5

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 7100

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human TLR5 (NP_003259.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O60602

Santa Cruz:

Calculated MW: 97 kDa

Observed MW: 100 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TLR5 Polyclonal Antibody DataSheet