TNFRSF13C Polyclonal Antibody | G-AB-03258
Gentaur Antibodies
- SKU:
- G-AB-03258
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
TNFRSF13C Polyclonal Antibody | G-AB-03258 | Gentaur Antibodies
Overview: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE) . Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Signal Transduction
Synonyms: B cell activating factor receptor, B-cell-activating factor receptor, BAFF R, BAFF receptor, BAFF-R, BAFFR, BLyS receptor 3, BlySR3, BR 3, BR3, BROMIX, CD 268, CD268, CD268 antigen, CVID4, MGC138235, OTTHUMP00000028746, Prolixin, TNFRSF 13C, Tnfrsf13c, TR13C, Tumor necrosis factor receptor subunit member 13C, Tumor necrosis factor receptor superfamily member 13C
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_443177
Clonality: Polyclonal
Immunogen: Synthetic peptide of human TNFRSF13C
Clone #:
Conjugation: Unconjugated
Swissprot: Q96RJ3
Santa Cruz: sc-19886/sc-28988
Calculated MW:
Observed MW:
Concentration: 0.7 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.