TNFSF12 Polyclonal Antibody | G-AB-09440

TNFSF12 Polyclonal Antibody | G-AB-09440 | Gentaur Antibodies

Overview: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology

Synonyms: TNFSF12, APO3L, DR3LG, TNLG4A, TWEAK

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8742

Accession #:

Clonality:

Immunogen: Recombinant protein of human TNFSF12

Clone #:

Conjugation: Unconjugated

Swissprot: O43508

Santa Cruz:

Calculated MW: 27 kDa/36 kDa

Observed MW: 27 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TNFSF12 Polyclonal Antibody DataSheet