TPP1 Polyclonal Antibody | G-AB-10745

TPP1 Polyclonal Antibody | G-AB-10745 | Gentaur Antibodies

Overview: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Neuroscience

Synonyms: TPP1, CLN2, GIG1, LPIC, SCAR7, TPP-1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 1200

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human TPP1 (NP_000382.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: O14773

Santa Cruz:

Calculated MW: 34 kDa/61 kDa

Observed MW: 50 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TPP1 Polyclonal Antibody DataSheet