TRAF3 Polyclonal Antibody | G-AB-07246

TRAF3 Polyclonal Antibody | G-AB-07246 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the Signal Transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the Signal Transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology, Signal Transduction

Synonyms: TRAF3, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 7187

Accession #:

Clonality:

Immunogen: A synthetic peptide of human TRAF3 (NP_003291.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13114

Santa Cruz:

Calculated MW: 55 kDa/64 kDa

Observed MW: 64 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:200-1:1000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TRAF3 Polyclonal Antibody DataSheet