TTI1 Polyclonal Antibody | G-AB-03494

TTI1 Polyclonal Antibody | G-AB-03494 | Gentaur Antibodies

Overview: Regulator of the DNA damage response (DDR) . Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR) , ultraviolet (UV) and mitomycin C (MMC) . Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

Category Type: Polyclonal Antibody

Research Areas: Cell biology, Epigenetics and Nuclear Signaling

Synonyms: smg-10, KIAA0406

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_055472

Clonality: Polyclonal

Immunogen: Synthetic peptide of human TTI1

Clone #:

Conjugation: Unconjugated

Swissprot: O43156

Santa Cruz: sc-85604/sc-85605

Calculated MW:

Observed MW:

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-150, ELISA 1:2000-10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TTI1 Polyclonal Antibody DataSheet