TXNRD1 Polyclonal Antibody | G-AB-09502

TXNRD1 Polyclonal Antibody | G-AB-09502 | Gentaur Antibodies

Overview: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS) , that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction, Cell Biology, Metabolism

Synonyms: TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 7296

Accession #:

Clonality:

Immunogen: Recombinant protein of human TXNRD1

Clone #:

Conjugation: Unconjugated

Swissprot: Q16881

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:100 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TXNRD1 Polyclonal Antibody DataSheet