TYMS Polyclonal Antibody | G-AB-07393
Gentaur Antibodies
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Gentaur Antibodies
TYMS Polyclonal Antibody | G-AB-07393
- SKU:
- G-AB-07393
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
TYMS Polyclonal Antibody | G-AB-07393 | Gentaur Antibodies
Overview: Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism
Synonyms: TYMS, HST422, TMS, TS
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 7298
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human TYMS (NP_001062.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P04818
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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