UBA3 Polyclonal Antibody | G-AB-08946

UBA3 Polyclonal Antibody | G-AB-08946 | Gentaur Antibodies

Overview: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: UBA3, NAE2, UBE1C, hUBA3

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 9039

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human UBA3 (NP_003959.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q8TBC4

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

UBA3 Polyclonal Antibody DataSheet