UBA7 Polyclonal Antibody | G-AB-06252

UBA7 Polyclonal Antibody | G-AB-06252 | Gentaur Antibodies

Overview: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML) /retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms: D8, MGC12713, UBA1, ubiquitin activating enzyme E1 homolog B, UBA1B, UBA7, UBA7, ubiquitin activating enzyme E1, UBA7, Ube 1L, UBE 2, UBE1L, UBE2, Ubiquitin activating enzyme 2, Ubiquitin activating enzyme E1 homolog, Ubiquitin Activating Enzyme E1 Like, Ubiquitin activating enzyme E1 related protein, Ubiquitin-activating enzyme 7, Ubiquitin-activating enzyme E1 homolog, ubiquitin-activating enzyme-2, ubiquitin-like modifier activating enzyme 7, Ubiquitin-like modifier-activating enzyme 7

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC006378

Clonality: Polyclonal

Immunogen: Fusion protein of human UBA7

Clone #:

Conjugation: Unconjugated

Swissprot: P41226

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

UBA7 Polyclonal Antibody DataSheet