UBE2D1 Polyclonal Antibody | G-AB-09850

UBE2D1 Polyclonal Antibody | G-AB-09850 | Gentaur Antibodies

Overview: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT) , and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms: UBE2D1, E2 (17) KB1, SFT, UBC4/5, UBCH5, UBCH5A

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 7321

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human UBE2D1 (NP_003329.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P51668

Santa Cruz:

Calculated MW: 16 kDa

Observed MW: 14 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

UBE2D1 Polyclonal Antibody DataSheet