WISP2 Polyclonal Antibody | G-AB-07842

WISP2 Polyclonal Antibody | G-AB-07842 | Gentaur Antibodies

Overview: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Stem Cells

Synonyms: WISP2, CCN5, CT58, CTGF-L

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8839

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human WISP2 (NP_003872.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O76076

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

WISP2 Polyclonal Antibody DataSheet