XRN1 Polyclonal Antibody | G-AB-07072

XRN1 Polyclonal Antibody | G-AB-07072 | Gentaur Antibodies

Overview: This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: 5'-3' Exoribonuclease 1, SEP1, EC 3.1.13.-

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP061874

Clonality: Polyclonal

Immunogen: Synthetic peptide of human XRN1

Clone #:

Conjugation: Unconjugated

Swissprot: Q8IZH2

Santa Cruz:

Calculated MW: 194 kDa

Observed MW: Refer to figures

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:10-1:50, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

XRN1 Polyclonal Antibody DataSheet