ZBTB10 Polyclonal Antibody | G-AB-05153

ZBTB10 Polyclonal Antibody | G-AB-05153 | Gentaur Antibodies

Overview: RINZF, also known as ZBTB10 (zinc finger and BTB domain containing protein 10) , is a 847 amino acid protein that contains one BTB/POZ domain and two C2H2-type zinc fingers. Localized to the nucleus, RINZF is believed to play a role in transcriptional regulation. Specifically, RINZF is capable of binding to the CACC element of the Gastrin promoter. In this regard, RINZF competes with Sp1 for CACC binding and interferes with Sp1 transactivation, thereby regulating Gastrin gene expression. The rat RINZF protein shares 98% homology with the human RINZF protein, suggesting that RINZF is a conserved protein. Due to alternative splicing events, two RINZF isoforms exist. In addition, RINZF may be phosphorylated by ATR or ATM upon DNA damage.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: FLJ12752, OTTHUMP00000207119, RINZF, RINZFC, ZBT10, ZBTB10, Zinc finger and BTB domain containing protein 10, Zinc finger and BTB domain-containing protein 10, Zinc finger protein RIN ZF

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP001099009

Clonality: Polyclonal

Immunogen: Synthetic peptide of human ZBTB10

Clone #:

Conjugation: Unconjugated

Swissprot: Q96DT7

Santa Cruz:

Calculated MW: 95 kDa

Observed MW: Refer to figures

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000, ELISA 1:2000-1:5000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ZBTB10 Polyclonal Antibody DataSheet