ZC3H7A Polyclonal Antibody | G-AB-08095

ZC3H7A Polyclonal Antibody | G-AB-08095 | Gentaur Antibodies

Overview: The zinc finger CCCH domain-containing protein 7A (ZC3H7A) , also known as ZC3H7, HSPC055 or ZC3HDC7, is a 971 amino acid protein that contains a C3H1-type zinc finger domain, three C3H1-type zinc fingers and three TPR repeats. Belonging to the ZC3H12 family, ZC3H7A localizes to the nucleus. Existing as two alternatively spliced isoforms, ZC3H7A is encoded by a gene located on human chromosome 16p13.13. Chromosome 16 makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: ZC3H7A, HSPC055, ZC3H7, ZC3HDC7

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 29066

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ZC3H7A (NP_054872.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q8IWR0

Santa Cruz:

Calculated MW: 19 kDa/110 kDa

Observed MW: 120 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ZC3H7A Polyclonal Antibody DataSheet