ADSL Polyclonal Antibody | G-AB-11004

ADSL Polyclonal Antibody | G-AB-11004 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP) . Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD) , a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: ADSL, AMPS, ASASE, ASL

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 158

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ADSL (NP_000017.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P30566

Santa Cruz:

Calculated MW: 48 kDa/54 kDa

Observed MW: 55 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:20-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ADSL Polyclonal Antibody DataSheet