ANK3 Polyclonal Antibody | G-AB-01587

ANK3 Polyclonal Antibody | G-AB-01587 | Gentaur Antibodies

Overview: Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience

Synonyms: ANK-3, ANK3, ANK3, ankyrin 3 (G) , Ankyrin 3, node of Ranvier (ankyrin G) , Ankyrin 3, node of Ranvier, Ankyrin G119, Ankyrin-3, Ankyrin-G, brain specific ankyrin G, CHANK3, FLJ45464, OTTHUMP00000217458, OTTHUMP00000217575, RP11 369L1.1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_001191332

Clonality: Polyclonal

Immunogen: Synthetic peptide of human ANK3

Clone #:

Conjugation: Unconjugated

Swissprot: Q12955

Santa Cruz: sc-31778/sc-31776/sc-28561

Calculated MW:

Observed MW:

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ANK3 Polyclonal Antibody DataSheet