APC Polyclonal Antibody | G-AB-03620
Gentaur Antibodies
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Gentaur Antibodies
APC Polyclonal Antibody | G-AB-03620
- SKU:
- G-AB-03620
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
APC Polyclonal Antibody | G-AB-03620 | Gentaur Antibodies
Overview: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP) , an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Neuroscience, Stem Cells
Synonyms: Adenomatous Polyposis Coli, Adenomatous polyposis coli protein, Apc, APC, CC1, Deleted in polyposis 2.5, DP2, DP2.5, DP3, FAP, FPC, GS, Protein APC
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP000029
Clonality: Polyclonal
Immunogen: Synthetic peptide of human APC
Clone #:
Conjugation: Unconjugated
Swissprot: P25054
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1.1 mg/mL
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification method: Antigen affinity purification
Application: IHC, ELISA
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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