APC Polyclonal Antibody | G-AB-10194

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$218.00 - $465.00
SKU:
G-AB-10194
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse
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APC Polyclonal Antibody | G-AB-10194 | Gentaur Antibodies

Overview: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP) , an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Neuroscience, Stem Cells

Synonyms: APC, BTPS2, DP2, DP2.5, DP3, GS, PPP1R46

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 324

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human APC (NP_000029.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P25054

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

APC Polyclonal Antibody DataSheet