APC Polyclonal Antibody | G-AB-10194
Gentaur Antibodies
- SKU:
- G-AB-10194
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
APC Polyclonal Antibody | G-AB-10194 | Gentaur Antibodies
Overview: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP) , an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Neuroscience, Stem Cells
Synonyms: APC, BTPS2, DP2, DP2.5, DP3, GS, PPP1R46
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 324
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human APC (NP_000029.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: P25054
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC, IF
Dilution: IHC 1:50-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.