AVEN Polyclonal Antibody | G-AB-02712
Gentaur Antibodies
- SKU:
- G-AB-02712
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
AVEN Polyclonal Antibody | G-AB-02712 | Gentaur Antibodies
Overview: AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1’s ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL) , AVEN expression may be a useful tool in prognosis prediction.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology
Synonyms: 1700013A01Rik, 1700056A21Rik, Apoptosis caspase activation inhibitor, AVEN, AVEN, Cell death regulator Aven, mAven L, mAven S, MGC124011, OTTMUSP00000016129, PDCD12, Programmed cell death 12, RP23-52C15.2
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_065104
Clonality: Polyclonal
Immunogen: Synthetic peptide of human AVEN
Clone #:
Conjugation: Unconjugated
Swissprot: Q9NQS1
Santa Cruz: sc-49885/sc-49888
Calculated MW: 39 kDa
Observed MW:
Concentration: 0.4 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, IHC, ELISA
Dilution: WB 1:500-1:2000, IHC 1:25-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.