AVEN Polyclonal Antibody | G-AB-02712

AVEN Polyclonal Antibody | G-AB-02712 | Gentaur Antibodies

Overview: AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1’s ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL) , AVEN expression may be a useful tool in prognosis prediction.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology

Synonyms: 1700013A01Rik, 1700056A21Rik, Apoptosis caspase activation inhibitor, AVEN, AVEN, Cell death regulator Aven, mAven L, mAven S, MGC124011, OTTMUSP00000016129, PDCD12, Programmed cell death 12, RP23-52C15.2

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_065104

Clonality: Polyclonal

Immunogen: Synthetic peptide of human AVEN

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NQS1

Santa Cruz: sc-49885/sc-49888

Calculated MW: 39 kDa

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

AVEN Polyclonal Antibody DataSheet