BECN1 Polyclonal Antibody | G-AB-05250

BECN1 Polyclonal Antibody | G-AB-05250 | Gentaur Antibodies

Overview: Beclin-1 (BECN1) , also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Microbiology, Signal Transduction

Synonyms: APG6, ATG 6, ATG6, ATG6 autophagy related 6 homolog, Bcl-2-interacting protein beclin, Beclin 1 (coiled coil moesin like BCL2 interacting protein) , Beclin 1 autophagy related, Beclin-1, Beclin1, BECN 1, Becn1, BECN1, Coiled coil myosin like BCL2 interacting protein, Coiled-coil myosin-like BCL2-interacting protein, GT197, Protein GT197, VPS 30, VPS30

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Beclin1

Clone #:

Conjugation: Unconjugated

Swissprot: Q14457, O88597, Q91XJ1

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 2.6 mg/mL

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:300-1:1000, IF 1:100-1:500

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BECN1 Polyclonal Antibody DataSheet