BEST1 Polyclonal Antibody | G-AB-08557
Gentaur Antibodies
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Gentaur Antibodies
BEST1 Polyclonal Antibody | G-AB-08557
- SKU:
- G-AB-08557
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
BEST1 Polyclonal Antibody | G-AB-08557 | Gentaur Antibodies
Overview: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2) , also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Neuroscience
Synonyms: BEST1, ARB, BEST, BMD, RP50, TU15B, VMD2
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 7439
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human BEST1 (NP_004174.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: O76090
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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