BRK1 Polyclonal Antibody | G-AB-09664

BRK1 Polyclonal Antibody | G-AB-09664 | Gentaur Antibodies

Overview: HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton. HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization. Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex. The WAVE complex includes five proteins, one of which is HSPC300, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent. Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, it is thought to have the same or similar functions in many different organisms.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: BRK1, C3orf10, HSPC300, MDS027, hHBrk1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 55845

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human BRK1 (NP_060932.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q8WUW1

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BRK1 Polyclonal Antibody DataSheet