CASP3 Polyclonal Antibody | G-AB-01900
Gentaur Antibodies
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Gentaur Antibodies
CASP3 Polyclonal Antibody | G-AB-01900
- SKU:
- G-AB-01900
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
CASP3 Polyclonal Antibody | G-AB-01900 | Gentaur Antibodies
Overview: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Metabolism, Neuroscience
Synonyms: A830040C14Rik, Apopain, CASP-3, CASP3, CASP3, Casp3a, Caspase 3, Caspase 3, apoptosis-related cysteine peptidase, Caspase 3, apoptosis-related cysteine protease, Caspase 3, apoptosis-related cysteine protease a, Caspase-3 subunit p12, CC3, CPP-32, CPP32, CPP32B, Cysteine protease CPP32, EC 3.4.22.56, LICE, mldy, OTTHUMP00000165052, OTTHUMP00000165053, OTTHUMP00000165054, PARP cleavage protease, Procaspase3, Protein Yama, SCA 1, SCA-1, SREBP cleavage activity 1, Yama
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC016926
Clonality: Polyclonal
Immunogen: Recombinant protein of human CASP3
Clone #:
Conjugation: Unconjugated
Swissprot: P42574
Santa Cruz: sc-22139/sc-22140/sc-1224/sc-1226/sc-1225/sc-6138/sc-98785/sc-7148
Calculated MW: 32 kDa
Observed MW:
Concentration: 0.5 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, IHC, ELISA
Dilution: WB 1:200-1:1000, IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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