CAST Polyclonal Antibody | G-AB-00860

CAST Polyclonal Antibody | G-AB-00860 | Gentaur Antibodies

Overview: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4) , and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Neuroscience

Synonyms: BS 17, Calpain inhibitor, Calpastatin, Cast, Heart type calpastatin, ICAL, MGC9402, Sperm BS 17 component, Sperm BS-17 component

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC013579

Clonality: Polyclonal

Immunogen: Recombinant protein of human CAST

Clone #:

Conjugation: Unconjugated

Swissprot: P20810

Santa Cruz: sc-7560/sc-20779

Calculated MW: 77 kDa

Observed MW:

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CAST Polyclonal Antibody DataSheet