Catenin beta Monoclonal Antibody | G-AB-05373

Catenin beta Monoclonal Antibody | G-AB-05373 | Gentaur Antibodies

Overview: CTNNB1, also known as β-Catenin, is an evolutionarily conserved, multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs, CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .

Category Type: Monoclonal Antibody

Research Areas: Cancer, Cardiovascular, Neuroscience, Signal Transduction, Stem Cells

Synonyms: Beta catenin, Beta-catenin, Cadherin associated protein, Catenin (cadherin associated protein) , beta 1, 88kDa, Catenin beta 1, Catenin beta-1, CATNB, CHBCAT, CTNB1, CTNNB, CTNNB1, DKFZp686D02253, FLJ25606, FLJ37923, OTTHUMP00000162082, OTTHUMP00000165222, OTTHUMP00000165223, OTTHUMP00000209288, OTTHUMP00000209289

Reactivity: Human, Mouse, Rat

Host: Mouse

Isotype: IgG

Gene ID:

Accession #:

Clonality: Monoclonal

Immunogen: Recombinant protein corresponding to Mouse β-catenin

Clone #: 4A3H3

Conjugation: Unconjugated

Swissprot: P35222, Q02248, Q9WU82

Santa Cruz:

Calculated MW: 92 kDa

Observed MW: 92 kDa

Concentration: 420 μg/mL

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:1000, IHC 1:100-1:500

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Catenin beta Monoclonal Antibody DataSheet