CD177 Polyclonal Antibody | G-AB-08348
Gentaur Antibodies
- SKU:
- G-AB-08348
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
CD177 Polyclonal Antibody | G-AB-08348 | Gentaur Antibodies
Overview: This gene encodes a glycosyl-phosphatidylinositol (GPI) -linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
Category Type: Polyclonal Antibody
Research Areas: Immunology
Synonyms: CD177, HNA-2a, HNA2A, NB1, NB1 GP, PRV-1, PRV1, NB1GP
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 57126
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human CD177 (NP_065139.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q8N6Q3
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.