CD177 Polyclonal Antibody | G-AB-11169

CD177 Polyclonal Antibody | G-AB-11169 | Gentaur Antibodies

Overview: This gene encodes a glycosyl-phosphatidylinositol (GPI) -linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

Category Type: Polyclonal Antibody

Research Areas: Immunology

Synonyms: CD177, HNA-2a, HNA2A, NB1, NB1 GP, PRV-1, PRV1, NB1GP

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 57126

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CD177 (NP_065139.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q8N6Q3

Santa Cruz:

Calculated MW: 15 kDa/27 kDa/46 kDa

Observed MW: 45 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CD177 Polyclonal Antibody DataSheet