CDK6 Polyclonal Antibody | G-AB-07222
Gentaur Antibodies
- SKU:
- G-AB-07222
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
CDK6 Polyclonal Antibody | G-AB-07222 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Synonyms: CDK6, MCPH12, PLSTIRE
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 1021
Accession #:
Clonality:
Immunogen: A synthetic peptide of human CDK6
Clone #:
Conjugation: Unconjugated
Swissprot: Q00534
Santa Cruz:
Calculated MW: 36 kDa
Observed MW: 37 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC
Dilution: WB 1:500-1:2000 IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.